In the News

 Several Investigators have been able to leverage their CRRN involvement and access to other CRRN platforms and investigators to obtain new grants and projects:

Dr. Shawn Aaron (Network Director) 7-year CIHR Foundation grant to study the prevalence and the burden of un-diagnosed asthma and COPD in Canadian communities. 

Dr. Andrea Gershon (Network Lead: Population Health) 5-year Foundation grant to develop an online risk calculator whereby patients entering their characteristics can determine their own risk of asthma or COPD exacerbation, as well as receive customized, detailed education on how to reduce this risk.

Dr. Don Sin (Network Lead: Biomarker Discovery) 7-year CIHR Foundation grant to study biomarkers in COPD and COPD exacerbations.

Dr. Bernard Thebaud 7-year CIHR Foundation grant to study cell-based therapies for lung disease.

Dr. Mohsen Satadsafavi (Network Lead: Health Economics Platform) 5-year operating grant for his network-based project entitled “Interventions for undiagnosed and early-stage COPD: Informing policy, practice, and research through an Evaluation Platform in COPD”

Recent Publications from Network Platforms: {CRRN investigators and trainees are in bold}

Aaron SD, Tan WC, Bourbeau J, Sin DD, Loves RH, MacNeil J, Whitmore GA; Canadian Respiratory Research Network. Diagnostic Instability and Reversals of COPD Diagnosis in Subjects with Mild to Moderate Airflow Obstruction. Am J Respir Crit Care Med. 196(3): 306-314, 2017

Carlsten C, Rider CF. “Traffic-related air pollution and allergic disease: an update in the context of global urbanization.” Curr Opin Allergy Clin Immunol. 2017 Apr; 17(2):85-59.  doi: 10.1097/ACI.0000000000000351.

DPI Capaldi, K Sheikh, RL Eddy, F Guo, S Svenningsen, P Nair, DG McCormack and G Parraga for the Canadian Respiratory Research Network. Free-breathing Functional Pulmonary MRI: Response to Bronchodilator and Bronchoprovocation in Severe Asthma Acad Radiol 2017 May 24 DOI: 10.1016/j.acra.2017.04.012

Elbehairy AF, Guenette JA, Faisal A, Ciavaglia CE, Webb KA, Jensen D, Ramsook AH, Neder JA, O’Donnell DE; on behalf of the Canadian Respiratory Research Network. Mechanisms of exertional dyspnea in symptomatic smokers without COPD. Eur Respir J 2016; 48: 695-705.

Gupta N, Pinto L, Benedetti A, Li PZ, Tan WC, Aaron SD, Chapman KR, FitzGerald JM, Hernandez P, Marciniuk DD, Maltais F, O'Donnell DE, Sin D, Walker BL, Bourbeau J; Canadian Respiratory Research Network and the CanCOLD Collaborative Research Group. The COPD Assessment Test: Can It Discriminate Across COPD Subpopulations? Chest. 2016 Nov;150(5):1069-1079.

H Piyadasa, A Altieri A , S Basu, J. Schwartz , AJ Halayko & N Mookherjee. A Biosignature for airway inflammation in a house dust mite-challenged murine model of allergic asthma. Biol Open 2016 Jan 6:5(2) 112-21.

Kendzerska T, To TM, Aaron SD, Lougheed MD, Sadatsafavi M, FitzGerald JM, Gershon AS, for the Canadian Respiratory Research Network (CRRN). The impact of a history of asthma on long-term outcomes of people with newly diagnosed chronic obstructive pulmonary disease: a population study. Journal of Allergy and Clinical Immunology. 2016 Sep 15;S0091-6749(16):30706-0.

Khakban A, Sin DD, FitzGerald JM, McManus B, Ng R, Hollander Z, Sadatsafavi M. The projected epidemic of COPD hospitalizations over the next 15 Years: a population based perspective. American Journal of Respiratory and Critical Care Medicine 2017;195:287-91.

O'Sullivan MJ, Gabriel E, Panariti A, Park CY, Ijpma G, Fredberg JJ, Lauzon AM, Martin JG. Epithelial Cells Induce a Cyclooxygenase-1-dependent Endogenous Reduction in Airway Smooth Muscle Contractile Phenotype. Am J Respir Cell Mol Biol. [Epub ahead of print] July 14 2017

Tavakoli H, FitzGerald JM, Chen W, Lynd L, Kendzerska T, Aaron S, Gershon A, Marra C, Sadatsafavi M; Canadian Respiratory Research Network. Ten-year trends in direct costs of asthma: a population-based study. Allergy. 2017 Feb;72(2):291-299.

To T, Zhu J, Larsen K, Simatovic J, Williams D, Gershon A, Lougheed MD, Licskai C, Chen H, Villeneuve PJ, Crighton E, Su Y, Sadatsafavi M, Carlsten C, Canadian Respiratory Research Network. “Progression from Asthma to Asthma and COPD Overlap Syndrome (ACOS): Is air pollution a risk factor?” Am J Respir Crit Care Med. 2016 Aug 15; 194(4):429-438. doi:10.1164/rccm.201510-1932OC.

Events

 CRRN 2018 AGM

  January 18-19, 2018
 Ottawa,
Lord Elgin Hotel